Issued2025-09-30

Executive Order 14355 – Unlocking Cures for Pediatric Cancer with Artificial Intelligence

Executive OrderFederal

Summary

Directs the Department of Health and Human Services, the National Institutes of Health, and other agencies to harness AI to accelerate pediatric cancer research and care. It expands federal support for the Childhood Cancer Data Initiative and encourages secure use of electronic health record and claims data to improve diagnostics, treatment discovery, and prevention.

Healthcare Implications

Providers and researchers can expect expanded funding opportunities, data access, and pilots for AI in oncology. Organizations should align their data governance with privacy and transparency requirements and strengthen validation and safety monitoring for pediatric AI tools.

Impact Level

Medium

Keywords

Clinical Quality & Efficacy; Privacy & Data; Transparency & Governance

Stakeholders

Regulators & Government; Developers & Vendors; Providers & Health Systems; Patients & Public