Issued2026-07-29

Best Practice Guide and Testing & Evaluation Framework for Agentic AI

Best Practice Guide / Testing & Evaluation FrameworkVoluntary

Summary

Provides consensus guidance and evaluation methods for healthcare AI agents that can plan and take actions across systems, addressing autonomy boundaries, permissions, identity and tool access, human verification, provenance, audit logging, escalation, failure modes, and ongoing monitoring.

Healthcare Implications

Healthcare organizations and developers should define which actions an agent may take, apply least-privilege access, preserve traceable records of inputs and actions, require human verification for consequential steps, test foreseeable failure modes, and establish escalation and monitoring processes before deployment.

Impact Level

Medium

Keywords

Transparency & Governance; Safety & Risk; Clinical Quality & Efficacy; Privacy & Data; Equity & Bias

Stakeholders

Providers & Health Systems; Patients & Public; Payers & Purchasers; Developers & Vendors; Regulators & Government